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US biotech firm Arcturus Therapeutics said it expects to start distributing its COVID-19 vaccine candidate in the first quarter of next year after early stage trials showed promising results. Another potential advantage, according to Payne: Arcturus is working on producing its vaccine as a powder. Arcturus Therapeutics has built a multicultural team, based in San Diego, CA, USA, We have an exciting COVID-19 vaccine candidate that we hope will make a positive difference in the pandemic, See our team describe what it means for them to help get a vaccine to protect people around the world-no matter where you are from, https://arcturusrx.com/wp-content/uploads/2020/07/JoePayne_LanguageProficiency_V3_1.mp4, https://arcturusrx.com/wp-content/uploads/2020/07/MaherA_LanguageProficiency_V3_1.mp4, https://arcturusrx.com/wp-content/uploads/2020/07/thumbnail_BelleBao.jpg,https://arcturusrx.com/wp-content/uploads/2020/07/BelleBao_LanguageProficiency__V3_1.mp4, https://arcturusrx.com/wp-content/uploads/2020/07/thumbnail_HowardYu.jpg,https://arcturusrx.com/wp-content/uploads/2020/07/HowardYu_LanguageProficiency_V3_1.mp4, https://arcturusrx.com/wp-content/uploads/2020/07/thumbnail_YurongGuo.jpg,https://arcturusrx.com/wp-content/uploads/2020/07/YurongGuo_LanguageProficiency_V3_1.mp4, 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Arcturus Therapeutics Announces New Appointments to its Board of Directors and Scientific Advisory Board, Arcturus Therapeutics Raises $1.3 Million in Series Seed Funding, With $1.3M in Seed Funding, Arcturus Adds to RNAi Hub in San Diego, RNAi therapeutics startup sets up shop at Janssen labs, closes $1.3M seed round, Janssen Labs-based Arcturus gets $1.3M boost for RNAi delivery tech, Startup Arcturus Pulls in $1.3M in Seed Money amid Renewed Interest in RNAi, Arcturus Therapeutics Acquires Cutting-Edge UNA Patent Estate from Marina Biotech, Arcturus Therapeutics Acquires Cutting-Edge UNA Patent Estate from Marina, San Diego upstart acquires RNA tech from cash-strapped Marina Biotech, San Diego Life Sciences Roundup: Vical, Fate, Arcturus, and More, Arcturus Therapeutics Acquires Patent Portfolio from Marina Biotech, Marina Sells UNA Patent Estate to Arcturus as It Looks to Resume Operations, GenomeWeb Acturus Closes $5M Series A Round, Aims for Clinic in '15 with RNAi Drug, RNAi firm raises $5M to develop and deliver drugs that turn off disease-causing genes, Arcturus Therapeutics Raises $5 Million in Series A Funding to Maintain its Momentum in Nominating Lead Clinical Candidate in 2014, San Diego's Arcturus Raises $5M for 'Best-in-Class' RNAi Technology, Arcturus rakes in $5M to back RNAi tech, nanoparticle delivery, Arcturus Therapeutics, Inc. to Present at the Biotech Showcase 2014, Arcturus Therapeutics, Inc. and Re-Appointment of Andy Sassine to the Board of Directors, Arcturus Therapeutics Announces $9.8 Million Registered Direct Offering of Common Stock, Arcturus Therapeutics to Present at Three Upcoming Investor Conferences, Arcturus Therapeutics to Report Corporate Overview and Financial Results on November 7th, Arcturus Therapeutics Expands Platform with STARR™ Technology, Arcturus Therapeutics Announces Third Quarter Financial Results and Provides Corporate Update, Arcturus Therapeutics Appoints Steve Hughes, M.D., as Chief Development Officer, Arcturus Therapeutics to Present at Two Investor Conferences in March, Arcturus Therapeutics to Report Fourth Quarter and Year-End 2019 Financial Results and Provide Corporate Update on March 11, Arcturus Therapeutics and Duke-NUS Medical School Partner to Develop a Coronavirus (COVID-19) Vaccine using STARR™ Technology, Arcturus COVID-19 Vaccine to Benefit from Duke-NUS Genetic Correlation System, Arcturus Therapeutics Announces Clinical Trial Timeline for its COVID-19 Vaccine, Arcturus Therapeutics Announces Allowance of IND & Approval of Clinical Trial Application (CTA) for ARCT-810, a First-in-Class Investigational mRNA Medicine to Treat Ornithine Transcarbamylase Deficiency, Arcturus Therapeutics Announces Proposed Public Offering of Common Stock, Arcturus Therapeutics Announces Pricing of $70.0 Million Public Offering of Common Stock, Arcturus Therapeutics Announces Closing of Public Offering and Full Exercise of Underwriters’ Option to Purchase Additional Shares, Arcturus Reports Positive Preclinical Data for its COVID-19 Vaccine Candidate, Arcturus Therapeutics and Catalent Announce Partnership to Manufacture mRNA-Based COVID-19 Vaccine, Arcturus Therapeutics to Report First Quarter 2020 Financial Results and Provide a Corporate Update on May 7, 2020, Arcturus Therapeutics Announces First Quarter 2020 Financial Results and Provides a Corporate Update, Arcturus Reports Additional Supportive Preclinical Data for its COVID-19 Vaccine Candidate (LUNAR-COV19), Ultragenyx Announces Exercise of Option to Purchase Additional Stock of Arcturus Therapeutics, Arcturus Therapeutics Announces First Healthy Volunteer Dosed in Phase 1 Study of ARCT-810 for Ornithine Transcarbamylase (OTC) Deficiency, Arcturus Therapeutics to Present at the Raymond James Human Health Innovation Virtual Conference, Arcturus Therapeutics to be Added to Russell 2000® Index, Arcturus Therapeutics Announces the Formation of its Vaccine Platform Scientific Advisory Board, Arcturus Therapeutics & Duke-NUS Received Approval to Proceed with Phase 1/2 Clinical Trial for COVID-19 Vaccine Candidate, LUNAR-COV19, Arcturus Therapeutics Announces Agreement with Israeli Ministry of Health to Supply COVID-19 Vaccine Candidate, LUNAR-COV19, Arcturus Therapeutics Announces Pricing of $173.0 Million Public Offering of Common Stock, Arcturus Therapeutics to Report Second Quarter 2020 Financial Results and Provide Corporate Update on August 10, 2020, Arcturus Therapeutics Appoints Lance Kurata as Chief Legal Officer, Arcturus Therapeutics Announces Second Quarter 2020 Financial Results and Provides a Corporate Update, Arcturus Therapeutics Announces that it has Initiated Dosing of its COVID-19 STARR™ mRNA Vaccine Candidate, LUNAR-COV19 (ARCT-021) in a Phase 1/2 study, Arcturus Therapeutics Executes Definitive Supply Agreement with the Israeli Ministry of Health, Arcturus Therapeutics Announces Preclinical Publication of its COVID-19 Vaccine Candidate, Arcturus Therapeutics to Present at Upcoming Investor and Scientific Conferences, Arcturus Therapeutics to Present at Guggenheim’s Vaccines and Infectious Diseases Conference, Arcturus Therapeutics Announces Completion of First Three Dose Escalation Cohorts in Phase 1 Study of ARCT-810, Therapeutic Candidate for Ornithine Transcarbamylase (OTC) Deficiency, Recipharm signs agreement with Arcturus Therapeutics to support the manufacture of LUNAR®-COV19 (ARCT-021) vaccine candidate, Arcturus Therapeutics to Report Third Quarter 2020 Financial Results and Provide Corporate Update on Nov 9, 2020, Arcturus Therapeutics Announces Positive Interim ARCT-021 (LUNAR-COV19) Phase 1/2 Study Results for Both Single Shot and Prime-boost Regimens, and Up to $220 Million in Additional Financial Commitments from Singapore, Arcturus Therapeutics Announces Third Quarter 2020 Financial Results and Positive Clinical Updates for ARCT-810 Phase I Study and Additional ARCT-021 Interim Data, Arcturus Therapeutics to Present at Upcoming Investor Conference, Arcturus Therapeutics Announces Initiation of Dosing ARCT-810 in Patients with Ornithine Transcarbamylase (OTC) Deficiency, Arcturus Therapeutics Announces Pricing of $150 Million Public Offering of Common Stock. San Dieguito schools plans to reopen next month despite state rules, challenges, District officials say they don’t know if they have enough staff to reopen schools; about 10 percent of teachers have requested leave, S. Korea returns a San Diegan’s 40-year-old favor with a COVID ‘survival box’, The once-struggling country reaches out with pandemic supplies as a token of its gratitude, As crisis deepens, hundreds of hotel rooms reserved for COVID-19 response go unused by San Diego County, Data shows San Diego near bottom of California counties in filling hotel rooms set aside under state relief program, Systemic racism in USDA makes Justice for Black Farmers Act long overdue, Jillian Hishaw, founder and CEO of F.A.R.M.S., a nonprofit providing aid and resources to rural and small farmers, formerly worked as an adjudicator with the U.S. Department of Agriculture’s Office of Civil Rights, and discusses new legislation aimed at correcting a legacy of racism within the USDA against Black farmers, San Diego neighborhood residents protest new church. Arcturus’s vaccine uses messenger RNA (mRNA) technology — a novel approach to vaccines which scientists hope will trigger the immune system to fight the virus. Upon entering the cytosol, the LUNAR® formulations then become trapped in the endosomes. The less vaccine each person needs, the more people can be vaccinated. Arcturus’ diverse pipeline of RNA therapeutic and vaccine candidates includes self-replicating mRNA vaccine programs for SARS-CoV-2 (COVID-19) and Influenza, and other programs to … Although this isn't necessarily a … Newsom, Amid continued confusion over the state’s COVID-19 stay-home order, state officials clarify that overnight stays are permitted for essential workers, but not for leisure guests for at least the next three weeks, SDG&E turns in the only bid for San Diego’s gas and electric franchises, New mayor pledges to keep options open on a final decision, Report: gov’t spyware targets phones of Al-Jazeera reporters, A cybersecurity watchdog says dozens of journalists at Al-Jazeera, the Qatari state-owned media company, have been targeted by advanced spyware, US airport traffic rising despite holiday travel warnings, More than 1 million people have passed through U.S. airport security checkpoints in each of the past two days in a sign that public health pleas to avoid holiday travel are being ignored, France joins a growing list of countries to ban travel to the U.K. amid concerns about a new COVID-19 strain, Germany says it’s banning flights from the UK starting at midnight in response to new virus variant, Mostly virus-free Kauai hit by pandemic after travel resumes, The small, tight-knit community of about 72,000 people on Hawaii’s rural island of Kauai spent the first seven months of the pandemic mostly sheltered from the viral storm, Germany say it’s planning to restrict travel to and from Britain because of the new virus variant. Xconomy article on Arcturus Therapeutics, Inc. GEN article on Arcturus Therapeutics Inc. Union Tribune article on Arcturus Therapeutics Inc. ... ARCTURUS THERAPEUTICS. Arcturus’ diverse pipeline of RNA therapeutic and vaccine candidates includes self-replicating mRNA vaccine programs for SARS-CoV-2 (COVID-19) and Influenza, and other programs to potentially treat Ornithine Transcarbamylase (OTC) Deficiency, Cystic Fibrosis, Cardiovascular Disease along with partnered programs including Glycogen Storage Disease Type 3, Hepatitis B Virus, and non-alcoholic … Get U-T Business in your inbox on Mondays. Subscribe to email newsletters from the Union-Tribune about news, sports, business, opinion and more. CEO Joe Payne joined TheStreet's Katherine Ross to … Arcturus Therapeutics Announces the Formation of its Vaccine Platform Scientific Advisory Board Renowned experts in virology, infectious disease, vaccine … You can’t, says Gov. Supervisor-elect Terra Lawson-Remer is one of three new members joining the San Diego County Board of Supervisors in January. Massachusetts biotech Moderna could soon follow suit. The Korea Herald News on Arcturus Therapeutics Inc. Arcturus Therapeutics Inc. is Listed in the Key Players List; Involved in Non Alcoholic Steatohepatitis Pipeline (NASH), Arcturus Therapeutics in the list of Cystic Fibrosis Key Companies, Pictures by Ernst and Young (Finalists for the Entrepreneur Of The Year 2017 Award® in San Diego), Arcturus Therapeutics to Receive Up to $3 Million from Cystic Fibrosis Foundation Therapeutics to Advance a Novel LUNAR-Formulated mRNA CFTR Therapeutic, Alcobra Ltd. and Arcturus Therapeutics, Inc. Agree to Merge, Webcast: Arcturus Merger w/Alcobra Conference Call, Arcturus Therapeutics, Inc. to Present at the Chardan Gene Therapy Conference, Arcturus Therapeutics Announces Strategic Collaboration with Johnson & Johnson Innovation to Discover and Develop RNA Medicines, Arcturus Therapeutics Announces Presentations at Conferences in November, Arcturus Therapeutics to Present at the 5th International mRNA Health Conference on Nov 1st, Arcturus Therapeutics to Present at the 2017 North American Cystic Fibrosis Conference on Nov 2nd, Arcturus Therapeutics to Present at NY/NJ CEO Conference on Nov 8th, Arcturus Therapeutics and Synthetic Genomics Announce Strategic Alliance to Develop Next-Generation Vaccines and Therapeutics, Arcturus Therapeutics to Host Key Opinion Leader Call on Advances in Delivery of Nucleic Acid Medicines on Tuesday, November 7, Arcturus Therapeutics Announces Completion of Merger with Alcobra Ltd. and Commences Trading on the Nasdaq Global Market, Arcturus Therapeutics Ltd., to Present at Genetic Rx Conference at Harvard Medical School (Dec 7th), in a Panel Discussion Called “Next Generation RNA Technologies”, Arcturus Therapeutics Appoints Four New Directors and Reaches Settlement Agreement with Founder Joseph E. Payne, Arcturus Therapeutics Announces Extraordinary General Meeting of Shareholders, Arcturus Announces Management Appointments; Company Founder Joseph E. Payne Reinstated as President and CEO, Arcturus Therapeutics to Present at the JMP Securities Life Sciences Conference, Arcturus Therapeutics Announces Results of Extraordinary General Meeting of Shareholders, Arcturus Therapeutics Announces Annual and Extraordinary General Meeting of Shareholders to Be Held on August 24, 2018, Arcturus Therapeutics Achieves Program Milestones and Refines Agreement with Cystic Fibrosis Foundation Therapeutics, Arcturus Therapeutics to Present at Three Investor Conferences in September, Arcturus Therapeutics Appoints Andrew Sassine as Interim Chief Financial Officer, Arcturus Therapeutics Announces Appointment of Ernst & Young LLP as the Company’s Independent Auditor, Arcturus Therapeutics Expands Management Team, Arcturus Therapeutics to Present at October Investor Conferences, Arcturus Therapeutics Reports Second Quarter 2018 Financial Results and Provides Corporate Update, Arcturus Therapeutics Hosts Ribbon Cutting Ceremony for its Research and Development Facility, Arcturus Therapeutics Provides Corporate Update and Reports Third Quarter 2018 Financial Results, Arcturus Therapeutics to Host a Key Opinion Leader Call on Ornithine Transcarbamylase (OTC) Deficiency on December 11, Arcturus Therapeutics to Develop ARCT-810 for Treatment of Ornithine Transcarbamylase (OTC) Deficiency, Arcturus Therapeutics Appoints Andrew Sassine as Chief Financial Officer, Arcturus Therapeutics Reassumes Full Worldwide Rights to ARCT-810, a Clinical Development Candidate for Ornithine Transcarbamylase (OTC) Deficiency, Arcturus Therapeutics to Present at Upcoming Investor Conferences, Arcturus Therapeutics Provides Corporate Update and Reports Fourth Quarter and Year End 2018 Financial Results, Arcturus Therapeutics Presenting Data for ARCT-810 and the Arcturus mRNA + LUNAR® Technology Platform at the 2019 Annual Meeting of TIDES: Oligonucleotide and Peptide Therapeutics, Arcturus Therapeutics Announces Redomiciliation to the United States as a Delaware Corporation, Ultragenyx and Arcturus Therapeutics Expand Existing Research Collaboration and License Agreement to Develop Additional Nucleic Acid Therapies for Rare Diseases, Arcturus Therapeutics Receives Orphan Drug Designation from the U.S. FDA for ARCT-810, for Treatment of Ornithine Transcarbamylase (OTC) Deficiency, Arcturus Therapeutics to Participate in Two Panels at the ROTH RNA Revolution Conference, Arcturus Therapeutics Receives up to $15 Million Commitment from the Cystic Fibrosis Foundation to Create mRNA Therapies to Treat Cystic Fibrosis Patients, Arcturus Therapeutics Announces $10.9 Million Registered Direct Offering of Common Stock, Arcturus Therapeutics Announces $2.3 Million Additional Registered Direct Offering of Common Stock, Arcturus to Report Corporate Overview and Financial Results on August 15, Arcturus Therapeutics Announces Second Quarter Financial Results and Provides a Corporate Update, Arcturus Therapeutics To Present at Two Investor Conferences in September, Arcturus Therapeutics Announces Appointment of Dr. Edward Holmes M.D. And Arcturus is banking on there being sustained demand for a COVID-19 vaccine even after the current crisis has ended. The biotech announced Monday that it’s offering nearly 1.37 million shares at $110 apiece and expects to close the offering this week. With increased acidity as the endosome ages, a pH-mediated disruption enables release of the RNA payload following rapid biodegradation of the LUNAR®components. U.S. biotech firm Arcturus Therapeutics said it expects to start distributing its COVID-19 vaccine candidate in the first quarter of next year after early stage trials showed promising results. Arcturus COVID-19 Vaccine Benefits From Duke -NUS Genetic Correlation System • Gene expression changes can be measured within the first 5 days following vaccination • Helps Arcturus learn more quickly about the LUNAR-COV19 efficacy and safety profile. About Arcturus Therapeutics Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) is a clinical-stage mRNA medicines and vaccines … Arcturus Therapeutics is developing a COVID-19 vaccine under the guidance of the Singapore Health Services Authority. Yosemite’s Ahwahnee Hotel under fire for hosting hundreds at Thanksgiving feast, ‘Healing is coming’: US health workers start getting vaccine, COVID-19 vaccine clears key hurdle in California and much of the West, COVID-19 vaccine shipments begin in historic US effort. Load more articles Why Shares of iBio, Marinus Pharmaceuticals, and Arcturus Therapeutics All Crashed on Tuesday Get ready for your week with the week’s top business stories from San Diego and California, in your inbox Monday mornings. Shares in Arcturus closed at $105.45 Thursday, up $16.40 for the day. The Humane Society says it is confident its program is in the animals’ best interests. A scientist at RNA medicines company Arcturus Therapeutics researches a vaccine for the novel coronavirus (COVID-19) at a laboratory in San Diego, Calif., March 17, 2020. That powder, which would be dissolved in liquid before use, could potentially stay in the fridge or even at room temperature for far longer than other, more finicky vaccines — such as Pfizer’s, which must be stored at minus 94 degrees Fahrenheit. The vaccine is currently in clinical trials in Singapore to test its safety and how well different doses galvanize the immune system. “No one knows the exact number, but there’s going to be a good number of vaccines that help address this immediate need of the pandemic,” said Payne in a September interview with the Union-Tribune. Arcturus Therapeutics claims: 'Millions of vaccine doses by year's end' Dr. Grossman of Arcturus: 'During animal trials, almost 100% of animals showed immune response." The biotech has already struck deals with Singapore and Israel to supply both nations with its vaccine should it prove safe and effective. But those symptoms will pass, Moderna asking US, European regulators to OK its virus shots, Moderna Inc. says it will ask U.S. and European regulators to allow emergency use of its COVID-19 vaccine as new study results confirm the shots offer strong protection, Yes, you can get COVID twice. Arcturus began those trials over the summer, in partnership with Singapore’s government. Arcturus expects to distribute coronavirus vaccine in early 2021 The California-based company's announcement came as Pfizer said its COVID-19 … Arcuturs has an mRNA vaccine. Arcturus plans to use the money to test and manufacture its experimental COVID-19 vaccine, which uses a snippet of the coronavirus’s genetic code to spark a protective immune system. 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